Design and Synthesis of Different Aryl Substituted 1,3,4-Oxadiazole-imidazo[1,5-a]pyridine Derivatives as Anticancer Agents

Dandamudi Srilaxmi and Alugubelli Gopi Reddy and Reddymasu Sireesha and Pasupuleti Visweswara Rao and M. Ravi Kiran and Deepti Kolli and Mandava Venkata Basaveswara Rao (2022) Design and Synthesis of Different Aryl Substituted 1,3,4-Oxadiazole-imidazo[1,5-a]pyridine Derivatives as Anticancer Agents. Russian Journal of General Chemistry, 92. pp. 891-897. ISSN 1070-3632 (P-ISSN) , 1608-3350 (E-ISSN)

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URL: https://www.pleiades.online/abstract/genchem/22/ge...

Abstract

A new series of 1,3,4-oxadiazole incorporated imidazo[1,5-a]pyridine derivatives was prepared. Anticancer activity of all the obtained compounds was investigated by employing MTT assay. Among them, six compounds showed most prominent anticancer activity than etoposide.

Item Type:	Article
Keyword:	Alpidem , Imidazo[1,5-a]pyridine , 1,3,4-oxadiazole , Zibotentan , Anticancer activity
Subjects:	R Medicine > RC Internal medicine > RC31-1245 Internal medicine > RC254-282 Neoplasms. Tumors. Oncology Including cancer and carcinogens R Medicine > RS Pharmacy and materia medica > RS153-441 Materia medica > RS400-431 Pharmaceutical chemistry
Department:	FACULTY > Faculty of Medicine and Health Sciences
Depositing User:	SAFRUDIN BIN DARUN -
Date Deposited:	29 Sep 2022 11:14
Last Modified:	29 Sep 2022 11:14
URI:	https://eprints.ums.edu.my/id/eprint/34182

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