Comprehensive study on transglycosylation of CGTase from various sources

Chin Hui Lim, Chin Hui Lim, Babak Rasti, Joko Sulistyo, Mansoor Abdul Hamid and Babak Rasti and Joko Sulistyo and Mansoor Abdul Hamid (2021) Comprehensive study on transglycosylation of CGTase from various sources. Heliyon, 7. pp. 1-16. ISSN 2405-8440

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URL: https://pubmed.ncbi.nlm.nih.gov/33665455/

Abstract

Transglycosylation is the in-vivo or in-vitro process of transferring glycosyl groups from a donor to an acceptor, which is usually performed by enzymatic reactions because of their simplicity, low steric hindrance, high regionspecificity, low production cost, and mild processing conditions. One of the enzymes commonly used in the transglycosylation reaction is cyclodextrin glucanotransferase (CGTase). The transglycosylated products, catalyzed by CGTase, are widely used in food additives, supplements, and personal care and cosmetic products. This is due to improvements in the solubility, stability, bioactivity and length of the synthesized products. This paper's focus is on the importance of enzymes used in the transglycosylation reaction, their characteristics and mechanism of action, sources and production yield, and donor and acceptor specificities. Moreover, the influence of intrinsic and extrinsic factors on the enzymatic reaction, catalysis of glycosidic linkages, and advantages of CGTase transglycosylation reactions are discussed in detail.

Item Type:	Article
Keyword:	Transglycosylation reaction, Cyclodextrin glucanotransferase, CGTase
Subjects:	Q Science > QP Physiology > QP1-(981) Physiology > QP501-801 Animal biochemistry R Medicine > RC Internal medicine > RC31-1245 Internal medicine T Technology > TP Chemical technology > TP1-1185 Chemical technology > TP250-261 Industrial electrochemistry
Department:	FACULTY > Faculty of Food Science and Nutrition
Depositing User:	ABDULLAH BIN SABUDIN -
Date Deposited:	17 Aug 2023 13:40
Last Modified:	17 Aug 2023 13:40
URI:	https://eprints.ums.edu.my/id/eprint/36469

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