The trends and hotspots of immunotherapy for metastatic colorectal cancer from 2013 to 2022: A bibliometric and visual analysis

Yifan Gong and Jianping Kang and Mingting Wang and Firdaus Hayati and Syed Sharizman Syed Abdul Rahim and Poh, Lucky Wah Goh (2024) The trends and hotspots of immunotherapy for metastatic colorectal cancer from 2013 to 2022: A bibliometric and visual analysis. Human Vaccines & Immunotherapeutics, 20 (1). pp. 1-13. ISSN 2164-5515

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URL: https://www.tandfonline.com/doi/full/10.1080/21645...

Abstract

An increasing body of research indicates that immunotherapy has demonstrated substantial effectiveness in the realm of metastatic colorectal cancer(mCRC), especially among patients with deficient mismatch repair (dMMR) or microsatellite instability-high (MSI-H) (dMMR/MSI-H mCRC). This study constitutes the inaugural bibliometric and visual analysis of immunotherapy related to mCRC during the last decade. Between 2013 and the conclusion of 2022, we screened 306 articles from Web of Science and subjected them to analysis using Cite Space and VOS viewer. The United States stood out as the primary contributor in this area, representing 33.33% of the publications, with China following closely at 24.51%. The most prolific institution has the lowest average citation rate. Sorbonne University were the most highly cited institutions. Notably, Frontiers In Oncology published the largest quantity of articles. Andre, Thierry, and Overman, Michael J. were prominent authors known for their prolific output and the high citation rates of their work. The focus areas in this field encompass “tumor microenvironment,” “liver metastasis,” “tumor-associated macrophages,” “combination therapy” and “gut microbiota.” Some keywords offer promise as potential biomarkers for evaluating the effectiveness of immunotherapeutic interventions.

Item Type:	Article
Keyword:	Metastatic colorectal cancer, Bibliometrics, Visual analysis, Microsatellite instability, Immunotherapy
Subjects:	R Medicine > RC Internal medicine > RC31-1245 Internal medicine > RC254-282 Neoplasms. Tumors. Oncology Including cancer and carcinogens R Medicine > RM Therapeutics. Pharmacology > RM1-950 Therapeutics. Pharmacology > RM270-282 Immunotherapy. Serotherapy
Department:	FACULTY > Faculty of Medicine and Health Sciences
Depositing User:	SITI AZIZAH BINTI IDRIS -
Date Deposited:	12 Jun 2024 10:20
Last Modified:	12 Jun 2024 10:20
URI:	https://eprints.ums.edu.my/id/eprint/38853

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