Metabolites and bioactivity of the marine xestospongia sponges (porifera, demospongiae, haplosclerida) of southeast Asian waters

Fikri Akmal Khodzori and Nurzafirah Mazlan and Chong, Wei Sheng and Ong, Kuan Hung and Kishneth Palaniveloo and Muhammad Dawood Shah (2023) Metabolites and bioactivity of the marine xestospongia sponges (porifera, demospongiae, haplosclerida) of southeast Asian waters. Biomolecules, 13. pp. 1-16.

	Text ABSTRACT.pdf Download (40kB)
	Text FULL TEXT.pdf Restricted to Registered users only Download (4MB) \| Request a copy

URL: https://www.mdpi.com/2218-273X/13/3/484

Abstract

Sponges are aquatic, spineless organisms that belong to the phylum Porifera. They come in three primary classes: Hexactinellidae, Demospongiae, and Calcarea. The Demospongiae class is the most dominant, making up over 90% of sponge species. One of the most widely studied genera within the Demospongiae class is Xestospongia, which is found across Southeast Asian waters. This genus is of particular interest due to the production of numerous primary and secondary metabolites with a wide range of biological potentials. In the current review, the antioxidant, anticancer, antiinflammatory, antibacterial, antiviral, antiparasitic, and cytotoxic properties of metabolites from several varieties of Southeast Asian Xestospongia spp. were discussed. A total of 40 metabolites of various natures, including alkaloids, fatty acids, steroids, and quinones, were highlighted in X. bergquistia, X. testudinaria, X. muta, X. exigua, X. ashmorica and X. vansoesti. The review aimed to display the bioactivity of Xestospongia metabolites and their potential for use in the pharmaceutical sector. Further research is needed to fully understand their bioactivities.

Item Type:	Article
Keyword:	Sponge, Demospongiae, Xestospongia, metabolites, bioactivity, Southeast Asian waters
Subjects:	G Geography. Anthropology. Recreation > GC Oceanography > GC1-1581 Oceanography > GC1000-1023 Marine resources. Applied oceanography Q Science > Q Science (General) > Q1-390 Science (General) > Q1-295 General
Department:	INSTITUTE > Borneo Marine Research Institute
Depositing User:	SITI AZIZAH BINTI IDRIS -
Date Deposited:	10 Dec 2024 15:01
Last Modified:	10 Dec 2024 15:01
URI:	https://eprints.ums.edu.my/id/eprint/42228

Actions (login required)

View Item