Epstein-Barr Virus-associated smooth muscle tumour: Two case reports

Nor Farahin Abdul Kahar and Noraini Mohd Dusa and Nor Haizura Abd Rani and Huzlinda Hussin (2024) Epstein-Barr Virus-associated smooth muscle tumour: Two case reports. Malaysian Journal of Medicine and Health Sciences, 20. pp. 1-4. ISSN 2636-9346

Text FULL TEXT.pdf Restricted to Registered users only Download (715kB) | Request a copy

Abstract

Epstein-Barr virus-associated smooth muscle tumour (EBV-SMT) is an intermediate mesenchymal neoplasm recognised in immunocompromised patients, including HIV-infected patients. EBV-SMT is challenging to diagnose since it occurs in various age groups and anatomical sites and presents with nonspecific symptoms. The diagnosis is further complicated by the similarity of its histopathological features with other spindle cell tumours. A clinical history of immunosuppression, immunohistochemistry study and association with Epstein-Barr virus (EBV) infection can aid in the diagnosis. Here, we reported two cases of EBV-SMT in two patients with HIV infection, emphasising the histomorphology features and immunohistochemical profile that help in the diagnosis.

Item Type:	Article
Keyword:	Epstein-barr virus, Smooth muscle tumour, Immunocompromised patient, EBV infections, EBV nuclear antigen
Subjects:	R Medicine > RC Internal medicine > RC31-1245 Internal medicine > RC254-282 Neoplasms. Tumors. Oncology Including cancer and carcinogens R Medicine > RC Internal medicine > RC31-1245 Internal medicine
Department:	FACULTY > Faculty of Medicine and Health Sciences
Depositing User:	ABDULLAH BIN SABUDIN -
Date Deposited:	16 May 2025 12:41
Last Modified:	16 May 2025 12:41
URI:	https://eprints.ums.edu.my/id/eprint/43743

Actions (login required)

View Item