Gas chromatography-mass spectrometry (gc­ms)-based metabolomics of strobilanthes crispus from Sabah

Nur Aina Zakaria (2015) Gas chromatography-mass spectrometry (gc­ms)-based metabolomics of strobilanthes crispus from Sabah. Masters thesis, Universiti Malaysia Sabah.

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Abstract

Strobilanthes crispus or locally known as "bayam karang", "pecah kaca", "jin batu" and "pecah beling" in Malaysia, has been traditionally used to boost immune system, treating kidney stones, treatment for diabetes mellitus, treatment of high blood pressure and treatment of wound. Studies examining the phytochemical constituents revealed that the leaves of this plant contain ester glycosidic compound of caffeic acid, p-voumaric acid, , vanilic acid, ferulic acid, syringic acids, a-sitosterol, campesterol, hexadecanoic acid, methylester, lupeol, phytol, stigmasterol, flavonoid compounds such as ( + )-catechin, (-)-epicatechin, rutin, and etc. While most of the literatures focused on the chemical compounds present in the leaves of 5. crispus, none have been reported for the phytochemical constituents of the whole 5. crispus plant including the leaf, stem, root and flower. The lacking of such information has created a gap for researchers to understand in detail the chemistry part of the plant hence causes the researchers lost a lot of important information when trying to identify, isolate and purify bioactive compounds from the plant. Thus, this study was carried out to profile the leaves, stems and roots of 5. crispus plants from Sabah using gas chromatography mass spectrometry (GC-MS) approach. It is found that nine bioactive compounds were present in leaf extracts, eight compounds in the stem extracts and seven compounds in the root extracts of 5. crispus. Overall, 13 bioactive phytoconstituent was found in this plant which are squalene, vitamin E, stigmasterol, campesterol, diisooctyl phthalase, gamma-tocopherol, beta-amyrin, beta-sitosterol, gammasitosterol, hexadecanoic acid, phytol, lupeol, and 9,12,15-0ctadecatrienoic acid, (Z, Z, Z). Further study such as quantification is needed to know the amount of each bioactive compound detected in the plant in future.

Item Type:	Thesis (Masters)
Keyword:	Strobilanthes crispus, Medicinal plants, Phytochemistry, GC-MS analysis, Bioactive compounds
Subjects:	Q Science > QK Botany > QK1-989 Botany > QK1-474.5 General Including geographical distribution
Depositing User:	DG MASNIAH AHMAD -
Date Deposited:	18 Jun 2025 10:35
Last Modified:	18 Jun 2025 10:35
URI:	https://eprints.ums.edu.my/id/eprint/44203

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