Paroxysmal autonomic instability with dystonia (PAID) syndrome: A rare occurrence

Vayara Perumall Vinodh and Sivakumaran Rajandran and Rajesh Kumar Muniandy and Pulivendhan Sellamuthu (2025) Paroxysmal autonomic instability with dystonia (PAID) syndrome: A rare occurrence. Gazi Medical Journal, 36. pp. 211-213. ISSN 2147-2092

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Abstract

Paroxysmal autonomic instability with dystonia (PAID) is still under- recognized in clinical settings due to its rarity. This syndrome may mimic certain life-threatening conditions. We present a rare case of PAID syndrome. A 45-year-old female was brought to the hospital with an altered level of consciousness. An urgent computed tomography of the brain was performed, and a diagnosis of obstructive hydrocephalus secondary to cerebellar hemorrhage was made. Her family refused major surgery but consented to cerebrospinal fluid diversion. However, after several days in the ward, she developed ventriculitis. She was successfully treated with intravenous ceftriaxone. After several weeks at home, she developed episodic attacks of hypertension, tachycardia, and diaphoresis with hyperthermia and diaphoresis. She also had episodes of restlessness and generalized dystonic movements. She was diagnosed with PAID syndrome, and treatment was initiated. Her symptoms were successfully treated after three days.

Item Type: Article
Keyword: Paroxysmal autonomic instability with dystonia (PAID), dystonia, ventriculitis
Subjects: R Medicine > RC Internal medicine > RC31-1245 Internal medicine > RC49-52 Psychosomatic medicine
R Medicine > RC Internal medicine > RC31-1245 Internal medicine > RC86-88.9 Medical emergencies. Critical care. Intensive care. First aid
Department: FACULTY > Faculty of Medicine and Health Sciences
Depositing User: JUNAINE JASNI -
Date Deposited: 29 Jul 2025 19:52
Last Modified: 29 Jul 2025 19:52
URI: https://eprints.ums.edu.my/id/eprint/44678

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