Successful assisted conception in a case of recalcitrant chronic urticaria treated with omalizumab: A case report

Dg Marshitah Pg Baharuddin and Ehab Helmy Abdel Malek Fahmy and Mohd Nazri Mohd Daud and Mohsen MA Abdelhafez and Ling Yien Hii and Sook Yee Michelle Voo and Wen Foong Tan (2025) Successful assisted conception in a case of recalcitrant chronic urticaria treated with omalizumab: A case report. Medical Journal of Malaysia Case Reports, 4 (1). pp. 65-68. ISSN 2948-3859

Text FULLTEXT.pdf Restricted to Registered users only Download (174kB) | Request a copy

Abstract

Chronic urticaria (CU) is a debilitating disease characterized by recurrent wheals, angioedema, or both, lasting for at least six weeks. Although self-limiting, it remains a challenging condition to manage, particularly in patients with specific comorbidities. We report the case of a 39-year-old woman with recalcitrant CU and polycystic ovarian syndrome (PCOS), along with a history of adverse obstetric events. Her CU was successfully treated with subcutaneous omalizumab, providing excellent symptom control and enhancing her quality of life. Subsequently, she underwent an uneventful assisted reproduction technology (ART) procedure with a meticulously timed, resulting in the birth of healthy twins. This case highlights the role of omalizumab in treating recalcitrant CU during the preconception period and its continuation throughout pregnancy. It also underscores the importance of a comprehensive multidisciplinary approach in achieving a successful outcome.

Item Type:	Article
Keyword:	Chronic urticaria, debilitating disease, pregnancy
Subjects:	R Medicine > RC Internal medicine > RC31-1245 Internal medicine > RC581-951 Specialties of internal medicine > RC648-665 Diseases of the endocrine glands. Clinical endocrinology R Medicine > RG Gynecology and obstetrics > RG1-991 Gynecology and obstetrics > RG500-991 Obstetrics > RG551-591 Pregnancy
Department:	FACULTY > Faculty of Medicine and Health Sciences
Depositing User:	JUNAINE JASNI -
Date Deposited:	21 Oct 2025 14:53
Last Modified:	21 Oct 2025 14:53
URI:	https://eprints.ums.edu.my/id/eprint/45499

Actions (login required)

View Item