Ultrasmall metal nanoclusters as efficient luminescent probes for bioimaging

Xinyue Dou and Sariah Saalah and Chel-Ken Chiam and Jianping Xie and Coswald Stephen Sipaut @ Mohd Nasri (2024) Ultrasmall metal nanoclusters as efficient luminescent probes for bioimaging. Journal of Materials Chemistry B, 13. pp. 1180-1194.

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Abstract

Ultrasmall metal nanoclusters (NCs, <2 nm) have emerged as a novel class of luminescent probes due to their atomically precise size and tailored physicochemical properties. The rapid advancements in the design and utilization of metal NC-based luminescent probes are facilitated by the atomic-level manipulation of metal NCs. This review article explores (i) the engineering of metal NCs’ functions for bioimaging applications, and (ii) the diverse uses of metal NCs in bioimaging. We begin by presenting an overview of the engineering functions of metal NCs as luminescent probes for bioimaging applications, highlighting key strategies for enhancing NCs’ luminescence, biocompatibility and targeting capabilities towards biological specimens. Our discussion then centers on the bioimaging applications of metal NCs in subcellular organelles, individual cells, tissues, and entire organs. Finally, we offer a perspective on the challenges and potential developments in the future use of metal NCs for bioimaging applications.

Item Type:	Article
Keyword:	Luminescent, bioimaging, entire organs,
Subjects:	Q Science > QC Physics > QC1-999 Physics > QC474-496.9 Radiation physics (General) R Medicine > RD Surgery > RD1-811 Surgery > RD120.6-129.8 Transplantation of organs, tissues, etc.
Department:	FACULTY > Faculty of Engineering
Depositing User:	JUNAINE JASNI -
Date Deposited:	06 Jan 2026 15:51
Last Modified:	06 Jan 2026 15:51
URI:	https://eprints.ums.edu.my/id/eprint/45816

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