Jaeyres Jani and Zainal Arifin Mustapha and Chin Kai Ling and Amabel Seow Ming Hui and Roddy Teo and Kamruddin Ahmed (2020) The whole genome sequence data analyses of a mycobacterium tuberculosis strain sbh321 isolated in Sabah, Malaysia, belongs to ural family of lineage 4.
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The whole genome sequence data analyses of a mycobacterium tuberculosis strain sbh321 isolated in Sabah, Malaysia, belongs to ural family of lineage 4-Abstract.pdf Download (65kB) |
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The whole genome sequence data analyses of a Mycobacterium tuberculosis strain SBH321 isolated in Sabah, Malaysia, belongs to Ural family of Lineage 4.pdf Restricted to Registered users only Download (701kB) | Request a copy |
Abstract
In 2019, 10 million new cases of tuberculosis have been re- ported worldwide. Our data reports genetic analyses of a My- cobacterium tuberculosis strain SBH321 isolated from a 31- year-old female with pulmonary tuberculosis. The genomic DNA of the strain was extracted from pure culture and sub- jected to sequencing using Illumina platform. M. tuberculosis strain SBH321 consists of 4,374,895 bp with G + C content of 65.59%. The comparative analysis by SNP-based phylogenetic analysis using maximum-likelihood method showed that our strain belonging to sublineage of the Ural family of Europe–America–Africa lineage (Lineage 4) and clustered with M. tuberculosis strain OFXR-4 from Taiwan. The whole genome sequence is deposited at DDBJ/ENA/GenBank under the ac- cession WCJH0 0 0 0 0 0 0 0 (SRR10230353).
| Item Type: | Article |
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| Additional Information: | Since Mycobacterium tuberculosis of the Ural family has never been reported in Malaysia, the whole genome sequence of this strain could provide fundamental knowledge and insight to- wards understanding its microbial activities. The data could be used in the examination of the molecular characteristics and genetic vari- ability of the M. tuberculosis strain which would benefit molecular epidemiologists. The data, an important source towards understanding the relationship between M. tubercu- losis strains from Sabah and other regions, could assist in developing informed policy in the design and implementation of tuberculosis control programme. |
| Keyword: | Mycobacterium tuberculosis , Whole genome sequencing , Next generation sequencing , Ural family , Sabah , Malaysia |
| Subjects: | Q Science > QR Microbiology > QR1-502 Microbiology R Medicine > RA Public aspects of medicine > RA1-1270 Public aspects of medicine > RA421-790.95 Public health. Hygiene. Preventive medicine |
| Department: | FACULTY > Faculty of Medicine and Health Sciences |
| Depositing User: | DG MASNIAH AHMAD - |
| Date Deposited: | 20 Sep 2021 08:47 |
| Last Modified: | 19 May 2023 10:58 |
| URI: | https://eprints.ums.edu.my/id/eprint/30677 |
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