A systematic review of the application of enzyme-based biosensors as a preliminary screening method for environmental monitoring and food safety

Mohd Khalizan Sabullah and Rahmath Abdullah and Roslina Jawan and Lucky Goh Poh Wah and Hartinie Marbawi and Syed Umar Faruq Syed Najmuddin and Jualang Azlan Gansau and Mohd Yunus Syukorb, Mohd Nazri Abdul Rahman (2024) A systematic review of the application of enzyme-based biosensors as a preliminary screening method for environmental monitoring and food safety. Jurnal Teknologi. pp. 1-10. ISSN 2180-3722

Text FULL TEXT.pdf Restricted to Registered users only Download (361kB) | Request a copy

Abstract

In this article, the latest discoveries in the development of biosensors based on enzyme inhibition are reviewed. Due to their excellent selectivity and sensitivity, they represent a significant alternative method to conventional analytical methods; which is a method of analysis that only relies on the generation of instrumentation data without any preliminary screening. Basically, biosensors are able to convert biological activity into a quantifiable signal. These enzyme inhibition-based biosensors have a wide range of applications in the fields of environmental safety, food safety, and clinical analysis since toxic substances containing heavy metals and pesticides are the most effective inhibitors of enzymes. This paper is aimed at exploring the methods used and the sensitivity to various inhibitors for biosensors based on the inhibition of enzymes such as glucose oxidase, urease, tyrosinase, cholinesterase, and other enzymes.

Item Type:	Article
Keyword:	Biosensor, reversible inhibitor, irreversible inhibitor, enzyme, lineweaverburk plot
Subjects:	T Technology > TP Chemical technology > TP1-1185 Chemical technology T Technology > TP Chemical technology > TP1-1185 Chemical technology > TP200-248 Chemicals: Manufacture, use, etc.
Department:	FACULTY > Faculty of Science and Natural Resources
Depositing User:	ABDULLAH BIN SABUDIN -
Date Deposited:	28 Apr 2025 15:57
Last Modified:	28 Apr 2025 15:57
URI:	https://eprints.ums.edu.my/id/eprint/43643

Actions (login required)

View Item